Severe vitamin B12 deficiency in a breast fed infant with pancytopenia.
نویسندگان
چکیده
We report the case of a 7-month-old breast fed infant who presented with a nose bleed and bruises. Investigation showed severe nutritional B12 deficiency anemia with a pancytopenia. It is important to take the nutritional history of both the infant and the mother for early prevention and treatment.
منابع مشابه
Vitamin B12 deficiency in a breast fed infant.
We report the case of a 5 month old breast fed infant who presented with a history of vomiting, pallor, and failure to thrive. Investigations showed severe nutritional vitamin B12 deficiency with a megaloblastic pancytopenia. This deficiency was due to low vitamin B12 concentrations in the maternal breast milk, and subsequent investigations showed maternal pernicious anaemia. Treatment of the i...
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Vitamin B12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. Animal protein is the major dietary source of vitamin B12. Deficiency of vitamin B12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. Two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...
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Vitamin B12 deficiency is a well-known cause of megaloblastic anaemia and pancytopenia. However, the incidence in pregnancy is rarely reported. We present a case of a 32-year old multigravid woman who was diagnosed with megaloblastic anaemia since 22 weeks gestation and progressed to develop severe pancytopenia at 30 weeks gestation. She was also diagnosed with vitamin B12 deficiency related to...
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INTRODUCTION Although vitamin B12 deficiency is a well-known cause of hematological and neuropsychiatric illness, the presentation of combined severe pancytopenia, demyelination and prominent psychiatric impairment is rare. CASE PRESENTATION We present a case of a previously healthy 55-year-old East African man with severe vitamin B12 deficiency (serum vitamin B12 22pmol/L) secondary to perni...
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1661 vitamin B12 than the control foetuses, showing that vitamin-Bl2 deficiency in the mother may seriously affect the vitamin-B12 stores of the foetus. It seems probable, therefore, that infants born of vitamin-B12-deficient mothers will start life with defective body stores of this vitamin, even though cord blood levels may not be very low. As was to be expected the levels in the breast milk ...
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ورودعنوان ژورنال:
- Journal of tropical pediatrics
دوره 57 1 شماره
صفحات -
تاریخ انتشار 2011